Recombinant virus vaccine for bluetongue disease in sheep.

Sero-prevalence of bluetongue disease in sheep in west and northwest provinces of Iran

The objective of this study was to describe the seroprevalence rates of bluetongue virus (BTV) in sheep in west and northwest provinces of Iran. Bluetongue virus, an economically important orbivirus of the Reoviridae family, causes a hemorrhagic disease mainly in sheep and occasionally in cattle and some species of deer. Bluetongue virus is transmitted between its mammalian hosts by ce...

Vesicular stomatitis virus replicon expressing the VP2 outer capsid protein of bluetongue virus serotype 8 induces complete protection of sheep against challenge infection

Bluetongue virus (BTV) is an arthropod-borne pathogen that causes an often fatal, hemorrhagic disease in ruminants. Different BTV serotypes occur throughout many temperate and tropical regions of the world. In 2006, BTV serotype 8 (BTV-8) emerged in Central and Northern Europe for the first time. Although this outbreak was eventually controlled using inactivated virus vaccines, the epidemic cau...

Serological survey of sheep in Iran for Type specific Antibody to Bluetongue virus

A monovalent attenuated serotype 2 bluetongue virus vaccine confers homologous protection in sheep.

An outbreak of bluetongue caused by bluetongue virus serotype 2 virus in certain Mediterranean countries during 1999/2000, presented an opportunity to produce a monovalent type 2 vaccine. Since no data have been published previously on the protection conferred by the current live attenuated bluetongue vaccine strains used in the polyvalent vaccine, a challenge experiment was performed to determ...

Serologic evidence of bluetongue infection in onehumped camels (Camelus dromedarius) in Kerman province, Iran

Herein, we presented the first report on bluetongue (BT) disease in 10 pregnant camels in a herd fromKerman province, Iran. All sera samples were tested serologically (AGID, C-ELISA). We also used the Razi-BK cell line, performed primary culture of ovine kidney and inoculated intravenously the embryonatedchicken eggs (ECE) to culture and isolate the BT virus. Efforts to culture and isolation of...